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Anti Wrinkle injections and Microblading: This article is intended to give honest and clear advice to our readers and does not promote prescription products. Anti Wrinkle injections or Microblading First? Dr. Hamilton would advise against having Anti-Wrinkle injections before microblading. These injections relax the muscles in the brow area and can affect the natural shape of your eyebrows. Your brows may temporarily droop or become slightly asymmetrical whilst the toxin is t