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Revitalise your skin with Polyneucleotides treatment for a smoother, youthful glow. Book your consultation today!

Unlock Your Skin’s True Potential
with PolyPhil Polynucleotides 

What if your skin could repair itself instead of just being filled? 

​Unlike traditional fillers, PolyPhil™polynucleotides work to improve your skin's quality and texture rather than adding volume or structure. 

PolyPhil contains purified DNA fragments (polynucleotides)which support your skin’s repair processe and encourages collagen & elastin production.

For the delicate under-eye area, Dr. Mark recommends PolyPhil. Because our skin is so thin here, hyaluronic acid fillers can look lumpy or uneven if not placed at the perfect depth.

Polynucleotides avoid this by focusing on cell repair and thickening the skin to provide a smoother, more refreshed look without the risk of puffiness.

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Experience the rejuvenating effects of DNA Polyneucleotide therapy – book now!

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Is PolyPhil Right for You?

If you prefer a natural, regenerative approach to skin improvement rather than immediate volume, PolyPhil could be exactly right for you. 

​🧬Natural looking results:

Ideal for patients who want to look "fresher" without looking like they’ve had work done.

💎Targeting tired eyes:

Excellent for treating dark circles and fine lines in the delicate eye area.

Skin quality concerns:

Ideal for improving crepey skin, large pores, dullness, or scarring on the face, neck, and hands.

🛡️Regenerative approach:

Perfect, if you prefer long-term skin health over the "instant fix" of traditional fillers

Refresh Tired Under-Eyes with polynucleotides
Book a Consultation !

PolyPhil Polynucelotides Range

PolyPhil : Designed for rejuvenation of the face, neck, décolletage and hands, this formulation contains 40mg/2ml of high-concentration, long-chain polynucleotides to stimulate collagen and improve elasticity.

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PolyPhil Eye : Specifically formulated for the delicate periorbital area, this product 15mg/2ml reduces dark circles, puffiness, and fine lines while revitalizing tired-looking eyes.

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PolyPhil Next : Ideal for mature or damaged skin, this formula combines 20mg/2ml of polynucleotides with 20mg/2ml of Hyaluronic Acid, specifically targeting deep wrinkles, stretch marks, and depressed scars.

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Why Choose PolyPhil?


🧬 Natural DNA Technology: Purified Salmon DNA fragments for deep, cellular-level repair.
💎 Boosts & Rejuvenates: Activates fibroblasts to increase collagen and reduce inflammation.
✨ Firmer Skin: Delivers intense hydration and a youthful, tighter appearance.
🛡️ Suitable for All Ages : Safe, rejuvenating choice for all skin types.

PolyPhil Eye 

  • Initial Course: 3 sessions (3–4 weeks apart)

  • Maintenance: One treatment every 6 months

  • Comfort: 20-minute numbing cream

  • Procedure: 2ml precise injections

  • Duration: ~20 minutes

  • Aftercare: Minor bumps, swelling, or bruising (24–72 hrs)

PolyPhil Eye or Fillers?

Standard fillers pull in water, often causing puffiness or a "heavy" look. PolyPhil Eye works differently—it repairs the skin without adding artificial volume.

Key Benefits

  • Reduces Puffiness: Diminishes under-eye bags.

  • Smooths Skin: Softens fine lines & crow’s feet.

  • Tightens & Firms: Reduces sagging on lower eyelids.

  • Improves Quality: Boosts collagen for a rested glow.

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 The PolyPhil Journey 

Treatment Protocol – Just 3 sessions, spaced 3–4 weeks apart, to fully "reboot" your skin’s regeneration.

 Stay Radiant – A 6-month maintenance touch-up keeps your collagen levels peaking year-round.

Total Comfort – We apply a medical-grade numbing cream for 20 minutes beforehand so you can relax during the process.

Precision Care – 2ml of high-purity polynucleotides are administered via quick, expert injections. 

After-Work Polish  – The procedure takes only 30 minutes

Glow-Down – You will see tiny blebs, slight swelling, or a little bruising, which last  24–72 hours.

Profhilo or PolyPhil Which is Actually Better?

Forget the "which is better" debate—it’s about your specific goals.

Think of it this way:

Profhilo is hydration, PolyPhil is regeneration. 

✨Choose Profhilo: for intense, deep hydration, and want to plump up dry, crepey skin.

✨Choose PolyPhil: to treat under-eye darkness, thin skin or laxity. 

The Verdict:  Profhilo offers faster, visible hydration, Polynucleotides work over time to repair tissue.
Dr. Mark’s Tip:  Alternate them for a comprehensive approach to both hydration and density.

Polynucleotide Prices

  • Dublin & Galway Clinic Special:

    • 3-Session Package: €850 (Regular price €1,050 - Save €200)

    • 2-Session Package: €600

    • Single Session: €350

  • Belfast Clinic Packages:

    • 3-Session Package: £750

    • 2-Session Package: £520

    • Single Session: £270 

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Restore your skins vitality with Polyneucleotides  Contact us to book your session today!

Polynucleotide Injections FAQ’s

Dublin Clinic:

84 Merrion Square South, 

Dublin  

D02 T882

(+353) 83 421 7939

✉  drmark@hamiltonfaceclinic.com

Dublin Clinic Hours: 

Thursdays 10.30 am- 9.00 pm

Galway Clinic:

Room 2, Top Floor, Town Park House, Tuam Rd, Galway, 

H91 YXN0

✆  (+353) 83 421 7939

drmark@hamiltonfaceclinic.com

Anti-Wrinkle Treatments in Galway

Galway Clinic Hours: 

First Tuesday & Wednesday of every month 10.00 am – 8.00 pm

Belfast Clinic:

15 Sandringham St, 

Belfast, 

BT9 7DR

✆ 0794 449 7884

belfast@hamiltonfaceclinic.com

Belfast Clinic Hours: 

Tuesdays 10.00 am- 7.00 pm

Medical & Advertising Disclaimer

The information provided on this website is for general informational purposes only and is not intended to constitute medical advice, diagnosis, or treatment.

All medical aesthetic treatments carry potential risks and benefits, and individual results may vary. No guarantees or assurances can be given regarding outcomes. Any reference to treatment effects or benefits is indicative only and should not be interpreted as a promise of results.

Suitability for treatment is determined following a full medical consultation, during which individual circumstances, medical history, and treatment options are discussed. Not all patients are suitable candidates for all procedures.

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